Talk:Amisulpride

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Summary sheet: Amisulpride

Amisulpride
Chemical Nomenclature
Common names	Amisulpride, Solian, Barhemsys
Systematic name	4-amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-ethylsulfonyl-2-methoxybenzamide
Class Membership
Psychoactive class	Antipsychotic
Chemical class	Benzamide
Routes of Administration
WARNING: Always start with lower doses due to differences between individual body weight, tolerance, metabolism, and personal sensitivity. See responsible use section. ⇣ Oral Dosage Bioavailability 48% Threshold 25 mg Light 50 - 100 mg Common 100 - 200 mg Strong 200 - 300 mg Heavy 300 mg + Duration Total 12 - 24 hours Onset 20 - 40 minutes Peak 1.5 - 6 hours Offset 8 - 12 hours After effects 24 - 48 hours DISCLAIMER: PW's dosage information is gathered from users and resources for educational purposes only. It is not a recommendation and should be verified with other sources for accuracy.
Interactions

Amisulpride (also known under brand names including Solian and Barhemsys) is a atypical antipsychotic substance of the benzamide class.

History and culture

This History and culture section is a stub. As a result, it may contain incomplete or wrong information. You can help by expanding it.

Chemistry

This chemistry section is incomplete. You can help by adding to it.

Amisulpride is the 4-position amino substitution of sulpiride which in turn is based on a benzamide core.

Pharmacology

Amisulpride primarily works by antagonising D₂ and D₃ dopamine receptors aswell as the 5-HT₇, 5-HT_2A and 5-HT_2B serotonin receptors.

It is also known to act as a GHB receptor agonist and Mu- Delta- Kappa-opioid agonist

Subjective effects

This subjective effects section is a stub. As such, it is still in progress and may contain incomplete or wrong information. You can help by expanding or correcting it.

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Physical effects

• • Sedation
  • Increased salivation
  • Headaches
  • Nausea
  • Vomiting
  • Dry mouth anti-cholinergic effect
  • Constipation anti-cholinergic effect
  • Increased prolactin potentially causing the absence of the menstrual cycle, breast enlargement, breast milk secretion not related to breastfeeding, impaired fertility, impotence, breast pain, etc

Cognitive effects

• • Thought deceleration
  • Thought acceleration contradictory side effect
  • Dream potentiation

Experience reports

There are currently 0 experience reports which describe the effects of this substance in our experience index.

Additional experience reports can be found here:

• Erowid Experience Vaults: Amisulpride

Toxicity and harm potential

This toxicity and harm potential section is a stub. As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it. Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Dangerous interactions

This dangerous interactions section is a stub. As such, it may contain incomplete or invalid information. You can help by expanding upon or correcting it.

Warning: Many psychoactive substances that are reasonably safe to use on their own can suddenly become dangerous and even life-threatening when combined with certain other substances. The following list provides some known dangerous interactions (although it is not guaranteed to include all of them).

Always conduct independent research (e.g. Google, DuckDuckGo, PubMed) to ensure that a combination of two or more substances is safe to consume. Some of the listed interactions have been sourced from TripSit.

Legal status

This legality section is a stub. As such, it may contain incomplete or wrong information. You can help by expanding it.

• Australia: Amisulpride is a Schedule 4 prescription only drug.
• Brazil: Amisulpride is a Class C1 prescription only drug.
• United Kingdom: Amisulpride is a prescription only drug.
• United States: Amisulpride is a prescription only drug.

See also

• Responsible use

External links

• Amisulpride (Wikipedia)
• Amisulpride (Isomer Design)
• Amisulpride (DrugBank)
• Amisulpride (Drugs.com)