Mephedrone/Summary

Main article: Mephedrone

Psychoactive class: Entactogen, Stimulants

Chemical class: Cathinone, Substituted cathinones

Oral

• Thresh				Common				Heavy
  15	-	50	-	100	-	200	-	300	mg
  		Light				Strong

• • Total: 4 - 8 hours
  • Onset: 15 - 45 minutes
  • Come up: 15 - 30 minutes
  • Peak: 2 - 4 hours
  • Offset: 30 - 90 minutes
  • Afterglow: 2 - 4 hours

Insufflated

• Thresh				Common				Heavy
  5	-	15	-	45	-	80	-	125	mg
  		Light				Strong

• • Total: 3 - 6 hours
  • Onset: 15 - 45 minutes
  • Come up: 15 - 30 minutes
  • Peak: 30 - 60 minutes
  • Offset: 30 - 90 minutes
  • Afterglow: 2 - 4 hours

Harm potential

• • Exact toxic dosage is unknown

Tolerance

• • Full tolerance is reached develops with prolonged and repeated use
  • Decreases to half after 3 - 7 days
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with all dopaminergic stimulants

Physical effects

• • Stimulation
• • Dehydration
  • Difficulty urinating
  • Increased blood pressure
  • Increased heart rate
  • Increased perspiration
  • Teeth grinding
  • Vasoconstriction
  • Vibrating vision

Visual effects

• • Time distortion

Cognitive effects

• • Cognitive euphoria
  • Compulsive redosing
  • Time distortion
• • Empathy, affection and sociability enhancement
  • Increased libido
  • Increased music appreciation
  • Motivation enhancement
• • Anxiety suppression
  • Disinhibition
  • Thought deceleration

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index