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Deliriant use is associated with highly uncomfortable and/or dangerous experiences.

Deliriants are highly unpredictable and may result in erratic behaviors, self-injury, hospitalization, or death. It should be noted that most individuals do not choose to repeat the experience due to its unpleasant nature.

Please use harm reduction practices if using this substance (e.g. starting with a low dose and always having a trip sitter). Refer to this section for more details.


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Summary sheet: Biperiden


Biperiden (often sold under the brand name Akineton, among others) is an anticholinergic substance used to treat Parkinson's disease and some antipsychotic-induced movement disorders. Taken in higher doses than those used clinically, it has deliriant effects.

History and culture

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As a result, it may contain incomplete or wrong information. You can help by expanding it.

Biperiden was invented in Germany in 1953 by Dr. W. Klavehn.[1] It became approved in the United States in 1959.[2]

It is on the World Health Organization's List of Essential Medicines, a list which catalogues the safest and most effective medicines needed in a health system.[3]

Subjective effects

Disclaimer: The effects listed below cite the Subjective Effect Index (SEI), an open research literature based on anecdotal user reports and the personal analyses of PsychonautWiki contributors. As a result, they should be viewed with a healthy degree of skepticism.

It is also worth noting that these effects will not necessarily occur in a predictable or reliable manner, although higher doses are more liable to induce the full spectrum of effects. Likewise, adverse effects become increasingly likely with higher doses and may include addiction, severe injury, or death ☠.

Cognitive effects

Visual effects

After effects
Aftereffects (3).svg

Toxicity and harm potential


This toxicity and harm potential section is a stub.

As a result, it may contain incomplete or even dangerously wrong information! You can help by expanding upon or correcting it.
Note: Always conduct independent research and use harm reduction practices if using this substance.

It is strongly recommended that one use harm reduction practices when using this substance.

Legal status

  • United States: Biperiden is a prescription only drug in the United States. It has been discontinued.[5][6]

See also

External links


  1. Espacenet patent search: Bibliographic data
  2. "Biperiden Hydrochloride". The American Society of Health-System Pharmacists. Archived from the original on 21 December 2016. Retrieved 8 December 2016. 
  3. World Health Organization (2019). World Health Organization model list of essential medicines: 21st list 2019. Geneva: World Health Organization. hdl:10665/325771Freely accessible. WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. 
  4. 4.00 4.01 4.02 4.03 4.04 4.05 4.06 4.07 4.08 4.09 4.10 "Biperiden Monograph for Professionals". 
  5. Drugs@FDA: oral biperiden HCl tablets
  6. Drugs@FDA: biperiden lactate injections