Fly agaric: Ibotenic acid decarboxylation to muscimol

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Fly agaric: Ibotenic acid decarboxylation to muscimol
800px-2006-10-25 Amanita muscaria crop.jpg
A. muscaria mushrooms in different stages of growth.
Taxonomical nomenclature
Kingdom Fungi
Phylum Basidiomycota
Class Agaricomycetes
Order Agaricales
Family Amanitaceae
Genus Amanita
Species A. muscaria
Common nomenclature
Common names Fly agaric, Fly amanita
Mycological Characteristics
Spore print White
Active constituents Muscimol, Ibotenic acid

This guide will help you to decarboxylate the relatively neurotoxic compound ibotenic acid, to muscimol. Both compounds are found naturally in Amanita muscaria.

  • Heat Amanita muscaria at 200 °F (93°C) for two hours,[1] or 100 °C for 1.5 hour.