Diphenhydramine/Summary

Main article: Diphenhydramine

Psychoactive class: Deliriant, Depressant

Chemical class: Ethanolamine

Oral

• Thresh				Common				Heavy
  25	-	100	-	200	-	400	-	700	mg
  		Light				Strong

• • Total: 3 - 10 hours
  • Onset: 30 - 90 minutes
  • Come up: 45 - 90 minutes
  • Peak: 1 - 4 hours
  • Offset: 2 - 6 hours

Harm potential

• • Produces dependence with chronic use
  • Fatal at amounts close to or exceeding 2 grams

Tolerance

• • Full tolerance is reached with repeated use
  • Returns to baseline after 1 - 2 weeks
  • Cross-tolerance with all deliriants

Physical effects

• • Cough suppression
  • Nausea suppression
  • Sedation
• • Abnormal heartbeat
  • Dehydration
  • Difficulty urinating
  • Dizziness
  • Frequent urination
  • Increased blood pressure
  • Increased bodily temperature
  • Increased heart rate
  • Increased perspiration
  • Itchiness
  • Muscle cramp
  • Muscle twitching
  • Nausea
  • Physical fatigue
  • Restless legs
  • Skin flushing
  • Temperature regulation suppression
  • Temporary erectile dysfunction

Visual effects

• • Brightness alteration
  • Drifting
  • Object activation
  • Object alteration
  • Time distortion
  • Visual haze
• • Pattern recognition suppression
  • Peripheral information misinterpretation
  • Visual acuity suppression
• • Autonomous entity
  • External hallucination
  • Internal hallucination
  • Object activation
  • Perspective hallucination
  • Settings, sceneries, and landscapes
  • Shadow people
  • Transformations
  • Unspeakable horrors

Cognitive effects

• • Cognitive dysphoria
  • Time distortion
• • Increased music appreciation
• • Disinhibition
  • Emotion suppression
  • Focus suppression
  • Memory suppression
  • Sleepiness
  • Thought deceleration

Auditory effects

• • Auditory acuity enhancement
  • Auditory acuity suppression
  • Auditory hallucination

Multi-sensory

• • Psychosis
  • Scenarios and plots

See also

• Responsible use
• Summary index
• Subjective effect index
• Psychoactive substance index